Organized at Des Moines and mustered in September 19, 1862. Ordered to St. Louis, Mo. Attached to Dept. Missouri to February, 1863. 2nd Brigade, 2nd Division, Army of Southeast Missouri, Dept. Missouri, to March, 1863. 2nd Brigade, 14th Division, 13th Army Corps, Dept. Tennessee, to July, 1863. 2nd Brigade, 1st Division, 13th Army Corps, Dept. Tennessee, to August, 1863, and Dept. of the Gulf to March, 1864. 1st Brigade, 1st Division, 13th Army Corps, Dept. Gulf, to June, 1864. 1st Brigade, 3rd Division, 19th Army Corps, Dept. Gulf, to August, 1864. 4th Brigade, 2nd Division, 19th Corps, Dept. Gulf, to December, 1864, 4th Brigade, Reserve Corps, Military Division West Mississippi, to February, 1865. 1st Brigade, 2nd Division, Reserve Corps, Middle Division West Mississippi, February, 1865. 1st Brigade, 2nd Division, 13th Army Corps, Military Division West Mississippi, to July, 1865.

SERVICE.--Duty at St. Louis, Camp Patterson and West Plains, Mo., until February, 1863. March via Thomasville and Eminence to Iron Mountain, Mo., February 9–26, and duty there until March 9. Moved to St. Genevieve March 9–12, thence to Milliken's Bend, La., March 22–27, and duty there until April 25. Movement on Bruinsburg and turning Grand Gulf April 25–30. Anderson's Hill April 30. Battle of Port Gibson May 1. Bayou Pierrie May 2–3. Battle of Champion's Hill May 16. Big Black River May 17. (A detachment of Regiment guard prisoners to Memphis, Tenn., May 18-June 10, and while en route to rejoin Brigade at Vicksburg, reinforced garrison at Milliken's Bend, La., June 5, and participated in repulse of McCullough's attack on Milliken's Bend June 6–7.) Siege of Vicksburg May 18-July 4. Advance on Jackson July 5–10. Siege of Jackson July 10–17. Ordered to the Dept. of the Gulf August 13. Duty at Carrollton, Brashear City and Berwick until October 3. Western Louisiana Campaign October 3-November 17. Expedition to New Iberia October 3–7, and to Vermillion Bayou October 8–30. Moved to Brazos Santiago, Texas, November 17–23. Fort Esperanza November 27–30. Duty at Indianola until March, 1864, and at Matagorda Island until May 4. Moved to New Orleans, La., thence to Join Banks on Red River, May 4–15. Joined at Simsport and retreat to Morganza May 16–22. Duty at Morganza until October. Simsport October 6. Moved to Duvall's Bluff October 12, and duty there and in Arkansas until January, 1865. Ordered to New Orleans, La., thence to Barrancas, Fla., February 17. Campaign against Mobile and its defenses March and April. Steele's march from Pensacola, Fla., to Blakely, Ala., March 21-April 2. Occupation of Canoe Station March 27. Siege of Fort Blakely April 2–9. Assault and capture of Fort Blakely April 9. Occupation of Mobile April 12, and duty there until June. At Columbus until July. Mustered out July 26, 1865.